Tummy: The stomach is the commonest site of injection for Zepbound as a result of accessibility and the considerable fatty layer beneath the skin. When administering Zepbound into your abdomen, inject no less than 2 inches from the belly button as it's got a connective tissue named fascia that can't take in medication. The realm below your ribs and above the hip is the greatest location inside the abdomen to inject Zepbound.
Significant hypersensitivity reactions such as anaphylaxis and angioedema have been described with tirzepatide.
Suggest patients who are using oral hormonal contraceptives switch to a non-oral contraceptive technique, or include a barrier means of contraception, for 4 months right after initiation with Zepbound and for 4 months following Each individual dose escalation. Zepbound delays gastric emptying, so it may make oral contraceptives fewer productive.one
Zepbound works by minimizing calorie intake probable by impacting appetite1, and cutting down body fat with bigger Fats mass decline than lean mass loss1.
When the injection is sealed and it has a clear foundation, take out The grey protection deal with to open it. Discard the gray foundation cap as Placing it on yet again can damage the needle. Usually do not contact or thoroughly clean drops of medication over the needle.
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*Side effects may perhaps vary and should be evaluated via the Health care company for proper administration.
Zepbound is contraindicated in individuals with a personal or relatives background of MTC or in clients with Males 2, As well as in patients with acknowledged serious hypersensitivity to tirzepatide or any with the excipients in Zepbound.
Zepbound ought to not be frozen. Freezing the medication can change its composition, influencing how it may have an impact on The body. You may not get the specified final results with Zepbound when applying it frozen or thawed out.
Irrespective of whether you inject Zepbound by using the subcutaneous injection pen or vial, you need to clean the injection site to avoid infections. To start with, clean your palms or make use of a sanitizer.
Also, take the injection out of your refrigerator half-hour ahead of administering it to stay away from stinging.
14 sufferers per one hundred many years of publicity) compared to 0.two% of placebo-handled patients (0.15 people for each a hundred more info a long time of publicity). Zepbound has not been analyzed in individuals with a previous historical past of pancreatitis. It is mysterious if patients that has a background of pancreatitis are at better danger for enhancement of pancreatitis on Zepbound. Observe sufferers for signals and signs of pancreatitis, together with persistent extreme abdominal suffering often radiating into the back, which may or may not be accompanied by vomiting. If pancreatitis is suspected, discontinue Zepbound and initiate acceptable administration. If the diagnosis of pancreatitis is confirmed, Zepbound shouldn't be restarted.
If hypersensitivity reactions take place, advise clients to promptly request health-related interest and discontinue use of Zepbound. Tend not to use in people which has a prior really serious hypersensitivity reaction to tirzepatide or any with the excipients in Zepbound. Use caution in patients that has a background of angioedema or anaphylaxis with a GLP-1 receptor agonist because it is mysterious if this kind of sufferers might be predisposed to those reactions with Zepbound.
Your Zepbound pen will make two click on Seems when you push the purple button. The very first simply click signifies the injection get more info has commenced, Whilst the next click indicates that the injection has concluded. The complete method takes all over ten seconds.